Actively Recruiting
Observational Study of Sleep-disordered Breathing One Year After Lung Transplantation
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03
300
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Sleep-disordered breathing (SDB) involves repeated pauses in breathing during sleep, leading to daytime tiredness and reduced quality of life. This research focuses on people who have received a lung transplant, as they often face chronic health problems and weight gain that may affect sleep. The study aims to understand how common SDB is after lung transplantation and to explore its types and links to heart and lung health, kidney function, and graft failure. Participants will undergo diagnostic polysomnography, a sleep study, one year after their lung transplant to detect SDB and determine its type, whether central or obstructive. Researchers will also assess heart function with echocardiography, lung function, blood tests, and 24-hour blood pressure monitoring at the same time to examine how SDB relates to these factors. During the study, participants will be monitored one year post-transplant with sleep tests and various health assessments. The main measurement is the number of participants with SDB and its type at that time. Secondary outcomes include heart and lung function and blood pressure. The study involves no treatment intervention and focuses on observation and data collection over this period.
CONDITIONS
Brief Title
Sleep-disordered Breathing After Solid Organ Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 1 year after lung transplantation
You will not qualify if you...
- Refusal of polysomnography (sleep study)
- Medical condition preventing polysomnography (sleep study)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo diagnostic polysomnography and other assessments to evaluate sleep-disordered breathing and related clinical findings one year after lung transplantation.
1 visit (in-person)
Duration - Up to 1 year after transplantation
Participants are observed to evaluate the prevalence, incidence, and type of sleep-disordered breathing and its relationship with cardiovascular morbidity after lung transplantation.
Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Belgium, 3000
Actively Recruiting
Research Team
D
Dries Testelmans, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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