Actively Recruiting

Age: 18Years +
All Genders
ID03142022

Observational Study of Sleep-disordered Breathing One Year After Lung Transplantation

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03

300

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Sleep-disordered breathing (SDB) involves repeated pauses in breathing during sleep, leading to daytime tiredness and reduced quality of life. This research focuses on people who have received a lung transplant, as they often face chronic health problems and weight gain that may affect sleep. The study aims to understand how common SDB is after lung transplantation and to explore its types and links to heart and lung health, kidney function, and graft failure. Participants will undergo diagnostic polysomnography, a sleep study, one year after their lung transplant to detect SDB and determine its type, whether central or obstructive. Researchers will also assess heart function with echocardiography, lung function, blood tests, and 24-hour blood pressure monitoring at the same time to examine how SDB relates to these factors. During the study, participants will be monitored one year post-transplant with sleep tests and various health assessments. The main measurement is the number of participants with SDB and its type at that time. Secondary outcomes include heart and lung function and blood pressure. The study involves no treatment intervention and focuses on observation and data collection over this period.

CONDITIONS

Brief Title

Sleep-disordered Breathing After Solid Organ Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 1 year after lung transplantation
Not Eligible

You will not qualify if you...

  • Refusal of polysomnography (sleep study)
  • Medical condition preventing polysomnography (sleep study)

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - 1 day

Participants undergo diagnostic polysomnography and other assessments to evaluate sleep-disordered breathing and related clinical findings one year after lung transplantation.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 1 year after transplantation

Participants are observed to evaluate the prevalence, incidence, and type of sleep-disordered breathing and its relationship with cardiovascular morbidity after lung transplantation.

Trial Site Locations

Total: 1 location

1

UZ Leuven

Leuven, Belgium, 3000

Actively Recruiting

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Research Team

D

Dries Testelmans, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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