Internet-Based Cognitive Behavioral Therapy for Insomnia to Support Cognitive Health in Adults 65 and Older with Mild Cognitive Impairment

What this Trial Is About

Researchers are evaluating an Internet-delivered cognitive behavioral therapy for insomnia CBT-I to improve sleep and cognitive health in older adults with mild cognitive impairment and insomnia. This randomized controlled trial compares the CBT-I intervention to a patient education website, studying effects on sleep quality, daytime fatigue, quality of life, mood, and cognitive functions such as memory and attention. Participants are recruited online and must meet criteria for mild cognitive impairment and insomnia symptoms. Participants are randomly assigned to either the SHUTi OASIS online CBT-I program or a patient education website. The SHUTi program delivers tailored, interactive sleep therapy over 9 weeks, with new content released weekly and daily sleep diaries completed. The education group receives information about insomnia and CBT strategies all at once without tailoring. After the 9-week intervention, participants retain access to their assigned program for the study duration. Participants complete online cognitive tests, questionnaires, and sleep diaries at baseline, 9 weeks, then at 6, 12, 18, and 24 months. These assessments measure insomnia severity, sleep patterns, fatigue, quality of life, mood, and cognitive performance. The primary outcome is the Insomnia Severity Index, with additional measures including wake after sleep onset and sleep efficiency. The study lasts two years, with ongoing access to interventions and repeated assessments to track long-term effects.

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)