90-Day Trial of Neuralli Mood Supplement to Evaluate Stress, Sleep, Mood, and Burnout in Adults

What this Trial Is About

Researchers are evaluating the effects of a 90-day daily supplementation with Neuralli Mood, a probiotic and postbiotic dietary supplement, on adults experiencing psychological stress, occasional sleep disruption, anxiety, depressive symptoms, mood changes, happiness, and occupational burnout. This exploratory, open-label, single-group study uses participants as their own controls to gather preliminary evidence on these outcomes without a concurrent control group. Participants take two capsules of Neuralli Mood daily for 90 days, each dose containing 30 billion CFU of L. plantarum PS128 and 20 billion heat-treated cells of L. paracasei PS23. The supplement is taken with or without food at a consistent time. The study includes baseline assessments before starting supplementation and repeat assessments at the end of the 90-day period, along with scheduled check-ins for adherence, tolerability, and adverse event monitoring. During the study, participants complete validated self-report questionnaires assessing stress, sleep disturbance, mood, anxiety, depression, happiness, and burnout before and after the supplementation period. Researchers monitor safety and adherence throughout the 90 days. The primary outcomes focus on changes in stress and sleep disturbance scores, while secondary outcomes include measures of anxiety, depression, happiness, burnout, and treatment-emergent adverse events.

Sleep More, Stress Less: 90-Day Trial of Neuralli Mood