Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
NCT06976138

Sleep TO Prevent Post-surgical Pain

Led by Johns Hopkins University · Updated on 2025-06-18

252

Participants Needed

2

Research Sites

215 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research study is being done to compare different methods of addressing sleep problems before total knee replacement surgery. These methods include Cognitive Behavioral Therapy and light exposure.

CONDITIONS

Official Title

Sleep TO Prevent Post-surgical Pain

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • People with knee osteoarthritis
  • 60 years old and older
  • Scheduled to have unilateral (one knee) total knee replacement surgery for osteoarthritis
  • Have trouble falling or staying asleep
Not Eligible

You will not qualify if you...

  • Currently using medications to help sleep
  • Have completed Cognitive Behavioral Therapy for Insomnia
  • Used either Bright Light or Negative Ion exposures in the past year
  • Have an inflammatory rheumatologic disorder or seizure disorder
  • Have serious mental health disorder, Bipolar I disorder, or substance/alcohol use disorder
  • Have serious sleep or circadian rhythm disorder or untreated sleep apnea
  • Are pregnant or lactating
  • Have retinal pathology
  • History of eye surgery (Lasik or cataract okay if more than 3 months ago)
  • Are taking disease-modifying antirheumatic drugs
  • Taking photosensitizing medications
  • Are unwilling to discontinue over the counter sleep aids for at least 2 weeks before enrolling

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21224

Actively Recruiting

2

Mass General Brigham

Chestnut Hill, Massachusetts, United States, 02467

Active, Not Recruiting

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Research Team

A

Anna Kim-Dahl

CONTACT

M

Marise Owens

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Sleep TO Prevent Post-surgical Pain | DecenTrialz