Actively Recruiting
Sleep Restriction and Parental History of Hypertension
Led by Mayo Clinic · Updated on 2025-08-01
44
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
CONDITIONS
Official Title
Sleep Restriction and Parental History of Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adults aged 18-35 years
- No significant medical or psychiatric diseases
- Nonsmokers
- Nonpregnant
- Normal sleep duration (7-9 hours per night without habitual napping)
- Known hypertension status for both biological parents
- Ability to understand and comply with study procedures
- Ability to understand English and provide informed consent
You will not qualify if you...
- Younger than 18 or older than 35 years
- Body mass index less than 18.5 or 30 kg/m2 and above
- Pregnant or lactating
- Unknown hypertension status of biological parents or adopted
- Use of tobacco, vaping, marijuana, or other drugs
- Excessive caffeine intake (more than 400 mg/day)
- Excessive alcohol intake (more than 7 drinks/week for women, more than 14 drinks/week for men)
- High office or daytime ambulatory blood pressure (130/80 mmHg or higher)
- Fasting glucose 126 mg/dl or higher
- Reduced kidney function (glomerular filtration rate below 60 mL/min/BSA)
- History of significant medical or psychiatric disorders
- Regular use of prescription medications other than contraceptives
- Use of melatonin or other over-the-counter sleep aids
- Moderate-to-severe sleep disordered breathing or mild sleep disordered breathing with daytime sleepiness
- Moderate-to-severe insomnia
- Restless leg syndrome
- Excessive daytime sleepiness
- Extreme chronotype
- Night shift work
- Participation in other research studies
- Any medical, geographic, or social factor making participation impractical
- Not English-speaking or unable to provide informed consent
- Low hemoglobin levels excluding blood draws (women below 11.6 g/dL, men below 13.2 g/dL)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
S
Sabah Munir
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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