Actively Recruiting
Sleep-specific DBS Therapy in Parkinson's Disease
Led by University of Minnesota · Updated on 2026-03-03
64
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sleep-wake disturbances are a major factor associated with reduced quality of life of individuals with Parkinson's disease (PD), a progressive neurological disorder affecting millions of people in the U.S and worldwide. The brain mechanisms underlying these sleep disorders, and the effects of therapeutic interventions such as deep brain stimulation on sleep-related neuronal activity and sleep behavior, are not well understood. Results from this study will provide a better understanding of the brain circuitry involved in disordered sleep in PD and inform the development of targeted therapeutic interventions to treat sleep disorders in people with neurodegenerative disease.
CONDITIONS
Official Title
Sleep-specific DBS Therapy in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic Parkinson's disease
- At least 21 years old
- Existing or planned 7 Tesla brain imaging
- Planned surgery at University of Minnesota to implant DBS system in GPi or STN with directional leads as part of routine care
- Planned or completed bilateral DBS surgery in GPi or STN with directional leads at University of Minnesota, with initial programming session at least 2 weeks away
You will not qualify if you...
- Other significant neurological disorders
- History of dementia
- Post-operative complications or adverse effects affecting safety or study results
- Pregnant women
- Unsafe radiation exposure within the last year when combined with expected fluoroscopy dose for ECoG strip placement
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
E
Emily Weatherill, BS
CONTACT
L
Luke Johnson, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here