Actively Recruiting
Sleep, Stress and Migraine - an Observational and Training Study
Led by Susanne Wegener · Updated on 2026-05-07
80
Participants Needed
1
Research Sites
62 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The MiSleepS study investigates how sleep disturbances and stress are linked to migraine attacks. Participants wear a device called a WHOOP band, which tracks sleep and body signals, and answer brief daily questions via a smartphone app about their sleep, stress levels, and migraine symptoms. The goal is to identify personal patterns that may contribute to migraine. Based on these insights, participants receive individualized recommendations to improve their sleep and daily routines - aiming to reduce migraine attacks in the long term without medication. The study is conducted at the University Hospital Zurich and is aimed at adults with episodic migraine.
CONDITIONS
Official Title
Sleep, Stress and Migraine - an Observational and Training Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged between 18 and 65 years
- Diagnosed with episodic migraine according to ICHD-3 criteria confirmed by headache specialists
- Experience 4 to 14 headache days per month based on the 3 months before enrollment
- Able to give informed consent and follow the study protocol
- Sufficient German language skills to complete study procedures and questions
- On a stable migraine medication regimen for at least 3 months prior and during the study
You will not qualify if you...
- Diagnosed sleep disorders interfering with the intervention, including obstructive sleep apnea with apnea-hypopnea index > 15, restless legs syndrome, frequent NREM parasomnia, or REM behavior disorder
- Current inadequately treated or therapy-resistant psychiatric disorders that may affect participation, such as schizophrenia, bipolar disorder type I, PTSD with active symptoms, or major depressive disorder with ongoing impairment
- Regular use of benzodiazepines or other central nervous system depressants
- Use of steroid medications
- Known or suspected alcohol, drug, or medication abuse exceeding specified limits
- Unable to follow study procedures due to language, cognitive, or unstable home situations
- Participation in other drug or behavioral intervention studies within 3 months prior or during this study
- Planned medical interventions requiring hospitalization over 24 hours during the study
- Night shift work
- Travel across more than 2 time zones within one month before or during the study
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Zurich, Department of Neurology
Zurich, Switzerland, 8091
Actively Recruiting
Research Team
S
Susanne Wegener
CONTACT
M
Marie Therese Kleinsorge
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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