Study of Sleep and Stress Effects on Migraine in Adults Using Wearable Technology and Personalized Behavioral Plans

What this Trial Is About

Researchers are investigating how sleep disturbances and stress are linked to migraine attacks in adults with episodic migraine. This study aims to identify personal patterns that may trigger migraines by continuously monitoring sleep and body signals using a WHOOP wearable device, alongside daily smartphone app questions about sleep, stress, and migraine symptoms. The research also explores sex- and gender-related differences in migraine and response to behavioral changes, aiming to develop individualized, non-drug strategies to help reduce migraine attacks over time. Participants will first undergo a five-week observational phase where their natural sleep, stress, and migraine interactions are tracked without any intervention. After analyzing this data, participants are grouped based on their sleep-stress profiles and receive tailored behavioral recommendations targeting their specific patterns during a six-week intervention phase. A small control group follows the same monitoring but does not receive personalized advice to help separate effects of increased self-awareness from the intervention. Throughout the study, participants will wear the WHOOP device and use the app daily to report symptoms and behaviors. Researchers will measure changes in migraine days, migraine severity, sleep quality, stress levels, and adherence to recommendations. The study includes remote follow-ups and lasts about 11 weeks in total, with additional assessment of long-term migraine changes at three months. Safety and progress are closely monitored without medication changes during the study period.

Sleep, Stress and Migraine - an Observational and Training Study