Actively Recruiting

Age: 18Years +
All Genders
NCT07472686

Small Bowel Capsule Endoscopy in Lynch Syndrome

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-03-16

400

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown. The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screening of small bowel (pre)neoplastic lesions between January 1st 2000 and December 31 2024.

CONDITIONS

Official Title

Small Bowel Capsule Endoscopy in Lynch Syndrome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM)
  • Capsule endoscopy screening for (pre)neoplastic lesions of the small intestine
  • No opposition to the reuse of healthcare data for research purposes
Not Eligible

You will not qualify if you...

  • Absence of documented MMR gene variant
  • Opposition to the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Center for Digestive Endoscopy, Saint-Antoine Hospital

Paris, France

Actively Recruiting

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Research Team

X

Xavier DRAY, MD PhD

CONTACT

A

Aymeric BECQ, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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