Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06550284

Small Nerve Fiber Activity in Patients with Carpal Tunnel Syndrome Assessed Via Quantitative Sensory Testing

Led by Brooke Army Medical Center · Updated on 2025-02-05

48

Participants Needed

1

Research Sites

33 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The diagnosis of carpal tunnel syndrome (CTS) is typically based on clinical findings and confirmatory electrodiagnostic testing. However, electrodiagnostic testing can only assess large A-alpha and A-beta nerve fibers. Quantitative sensory testing (QST) is a series of tests used to assess small nerve fiber changes in the A-delta, c-fibers, and A-beta nerve fibers as well. Previous studies have used QST to assess small nerve fiber changes related to carpal tunnel syndrome and found changes compared to controls. This study will utilize a course of standard physical therapy care and assess for any changes to small nerve fiber activity and how those changes may or may not relate to patient outcomes.

CONDITIONS

Official Title

Small Nerve Fiber Activity in Patients with Carpal Tunnel Syndrome Assessed Via Quantitative Sensory Testing

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Pain and tingling in the median nerve area
  • Positive Phalen test
  • Positive Tinel test over the carpal tunnel
  • Willingness to attend physical therapy
Not Eligible

You will not qualify if you...

  • Signs of nerve root problems consistent with radiculopathy
  • Suspected involvement of radial or ulnar nerves based on monofilament testing
  • Bilateral carpal tunnel syndrome
  • Previous hand surgery
  • Injections in the upper body within the last 6 months
  • Trauma to cervical, shoulder, or upper extremity area in the last 6 months
  • Currently pregnant or postpartum within the last 6 months
  • Having had more than minimal care (evaluation and education only, 1 visit) for the current episode

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Brooke Army Medical Center

San Antonio, Texas, United States, 78234

Actively Recruiting

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Research Team

C

Cortney C Shewmaker, DPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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