Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06363266

A SMART Design to Optimize the Delivery of TEMPO - a Tailored, wEb-based Psychosocial and Physical Activity Self-Management Program for Men With Prostate Cancer and Their Caregivers

Led by St. Mary's Research Center, Canada · Updated on 2025-05-06

376

Participants Needed

2

Research Sites

95 weeks

Total Duration

On this page

Sponsors

S

St. Mary's Research Center, Canada

Lead Sponsor

P

Princess Margaret Hospital, Canada

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the TEMPO program, a self-directed, web-based psychosocial and physical activity management tool designed for men with prostate cancer and their family caregivers. The study aims to reduce anxiety and improve coping skills by addressing the physical and emotional challenges caused by prostate cancer and its treatment. This research uses a sequential multiple assignment randomized trial (SMART) design to find the most effective and cost-efficient way to deliver TEMPO, including options for additional guidance when needed. Participants will be randomly assigned to either use the TEMPO program or actively monitor their anxiety for 12 weeks. After this period, those still experiencing anxiety may receive extended TEMPO support or guidance through scheduled phone or online calls from trained non-health care professionals. The study includes two intervention stages, each lasting 12 weeks, with usual care continuing alongside the program. Active monitoring participants who need more support will gain access to TEMPO in the second stage. Throughout the study, participants complete surveys at baseline, 13 weeks, and 25 weeks to assess anxiety and other health outcomes like stress, self-efficacy, exercise habits, and coping. The research team tracks anxiety levels and evaluates the cost-effectiveness of TEMPO compared to active monitoring. The total participation time spans about 25 weeks, with data collected to understand the program's impact on both patients and caregivers.

CONDITIONS

Brief Title

A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with prostate cancer
  • Receiving or scheduled to receive treatment for prostate cancer (excluding active surveillance) within the past 2 years
  • Have a caregiver willing to participate
  • Report at least moderate anxiety (ESAS-r Anxiety score of 3 or higher)
  • Able to read English or French
  • Have access to the internet
Not Eligible

You will not qualify if you...

  • Currently hospitalized (for both patient and caregiver)

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening visit (in-person or phone) to complete eligibility assessment and consent

Treatment - Stage 1: TEMPO or Active Monitoring

Duration - 12 weeks

Participants are randomized to either use TEMPO, a web-based psychosocial and physical activity self-management program, or to active monitoring with usual care for 12 weeks.

Online baseline questionnaire and follow-up assessments at 12 weeks

Treatment - Stage 2: Continued TEMPO, Guided TEMPO, or TEMPO for Active Monitoring Non-responders

Duration - 13 weeks

After 12 weeks, participants using TEMPO who continue to experience anxiety are re-randomized to receive either continued self-directed TEMPO or TEMPO plus guidance through eight 20-minute phone or online calls. Participants initially in active monitoring who do not respond are stepped up to TEMPO. This stage lasts 13 weeks.

Eight guidance calls for those receiving guidance; ongoing access to TEMPO for others; follow-up assessments at 25 weeks

Trial Site Locations

Total: 2 locations

1

St Mary's Hospital Research Centre

Montreal, Canada, Canada

Actively Recruiting

2

St. Mary's Research Centre

Montreal, Quebec, Canada, H3T1M5

Actively Recruiting

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Research Team

S

Sylvie Lambert, PhD

M

Margit Fuchs, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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