Actively Recruiting
Smart Olfaction App to Reduce Relapse
Led by University of Houston · Updated on 2026-05-01
132
Participants Needed
1
Research Sites
70 weeks
Total Duration
On this page
Sponsors
U
University of Houston
Lead Sponsor
U
University of Pittsburgh
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed project aims to refine and test a novel biobehavioral smoking cessation intervention that integrates the strategic application of olfactory stimulation to reduce cigarette craving with an established smartphone-based smoking cessation application. The specific aims of this study are: (1) refine the design and methodology of our olfactory stimulation delivery system (OSDS) and (2) compare, in a pilot randomized controlled trial (RCT), the effects of a smartphone based app for smoking cessation (Smart-T) with and without the OSDS on smoking cessation outcomes.
CONDITIONS
Official Title
Smart Olfaction App to Reduce Relapse
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years of age
- Ability to read, understand and speak English
- Currently smoke at least 5 cigarettes daily for one year or longer
- Do not currently smoke marijuana or are willing to not smoke marijuana during the study
- Did not use electronic cigarettes or vaping devices in the past 90 days
- Have an active Apple or Android smartphone with phone service including a data plan
- Interested in downloading the study app onto their personal phone
- Motivated to quit smoking
- English literacy at 7th grade level or higher (score 6 4 on REALM-SF)
- Biochemical verification of smoking status
- Proof of smoking status at enrollment via photo of cigarettes
- Present a photo ID matching the screener information
- Willing and able to complete all study procedures
- Willing to use nicotine replacement therapy and quit smoking for 14 days (Phase I) or 13 weeks (Phase II)
You will not qualify if you...
- Olfactory dysfunction such as inability to smell, weak or distorted sense of smell, or sensitivity to odors
- Allergies or negative reactions to odors or fragranced products
- Pregnant, breastfeeding, or planning pregnancy within the next month
- Uncontrolled hypertension
- Heart attack within the past two weeks
- Participation in Phase I excludes eligibility for Phase II
- Smartphone not compatible with the Insight mHealth platform
- Use of electronic cigarettes or vaping devices in the past 90 days
- Cognitive impairment (score 6 8 on the Six-Item Cognitive Impairment Test)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
RESTORE Laboratory: Research on Emotion, Substance Use Treatment Outcomes, Rehabilitation, and Empowerment
Houston, Texas, United States, 77204
Actively Recruiting
Research Team
L
Lorra Garey, Ph.D.
CONTACT
M
Michael Businelle, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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