Actively Recruiting
Smoking Cessation CM for Veterans With or at Risk for Cancer
Led by VA Office of Research and Development · Updated on 2025-09-30
108
Participants Needed
1
Research Sites
347 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
U
University of California, San Francisco
Collaborating Sponsor
AI-Summary
What this Trial Is About
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking during lung cancer screening or cancer care at VA clinics. CM is a behavioral treatment that uses rewards to encourage smoking cessation when verified through biological testing. In the first year, the researchers will develop a mobile CM protocol based on feedback from Veterans and healthcare staff through focus groups. In the second year, they will conduct a pilot study to test the feasibility of the mobile CM program along with counseling and medication for 20 Veterans over a five-week period. The success of the pilot study will determine whether to proceed with a larger randomized controlled trial (RCT) in years three to six, comparing the efficacy of mobile CM with standard treatment. The project will take place at SFVA.
CONDITIONS
Official Title
Smoking Cessation CM for Veterans With or at Risk for Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Veteran eligible for VA healthcare
- English-speaking
- Received cancer monitoring, treatment, or lung cancer screening at San Francisco VA Healthcare System within the past 24 months
- Active cigarette smoking within the past 24 months
- Access to Wi-Fi and a device that supports audio and video communication
- Current medical care at San Francisco VA Healthcare System (at least one clinical visit the same calendar year for cancer)
- Current enrollment in VA lung cancer screening or current diagnosis of cancer confirmed in medical records
- Smoking at least 1 cigarette per day on average in the past 30 days
- Willing to receive smoking cessation interventions
You will not qualify if you...
- Current severe, untreated mental illness such as psychosis, bipolar disorder, or substance use disorder
- Active suicidal or homicidal thoughts or severe behavioral instability in the past 30 days
- Never smoked or quit smoking more than 36 months prior to consent
- No access to Wi-Fi or devices that support audio and video communication
- Unable to commit to 1.5 hours for focus group and questionnaires (for staff)
- Recent unstable psychiatric or medical conditions judged by the study investigator
- Untreated active problem gambling
- Metastatic cancer or enrolled in end-of-life or palliative care
- Unable to commit to the required time for study participation
- Currently pregnant or planning pregnancy during the study (ages 18-55)
- Suicide attempt or suicidal thoughts with intent in the past 30 days
- Concurrent enrollment in another tobacco cessation clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
San Francisco VA Medical Center, San Francisco, CA
San Francisco, California, United States, 94121-1563
Actively Recruiting
Research Team
E
Ellen Herbst, MD
CONTACT
M
Madeline Martinez Rivas, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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