Actively Recruiting
Social & Affective Cognition in Alzheimer's Disease & Associated Disorders
Led by University Hospital, Lille · Updated on 2026-04-30
120
Participants Needed
1
Research Sites
170 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Lille
Lead Sponsor
F
France Alzheimer
Collaborating Sponsor
AI-Summary
What this Trial Is About
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains.
CONDITIONS
Official Title
Social & Affective Cognition in Alzheimer's Disease & Associated Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women
- Between 40 and 85 years of age
- Registered with the French Social Security
- Have a study partner who can complete behavioral questionnaires
- Fluent in French, able to read and write
You will not qualify if you...
- Contraindications for MRI scanning
- Significant sensory deficits not corrected by devices
- Dementia caused by non-neurodegenerative diseases or severe cerebrovascular risk
- Other neurodegenerative diseases such as Lewy body dementia or Parkinson's disease
- Serious neurological disorders including brain tumor, stroke, epilepsy, hydrocephalus
- Excessive alcohol intake or drug abuse
- Risk of non-compliance with study procedures as judged by investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lille University Hospital
Lille, France, 59000
Actively Recruiting
Research Team
T
Thibaud LEBOUVIER, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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