Actively Recruiting
Social Cognition in Patients With Amyotrophic Lateral Sclerosis
Led by University Hospital, Angers · Updated on 2026-03-05
74
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function. The clinical hallmark of Amyotrophic Lateral Sclerosis is the combination of upper and lower motor neuron signs and symptoms. The most recent studies suggest that up to 50% of Amyotrophic Lateral Sclerosis patients demonstrate mild to moderate cognitive disturbance. Impaired social cognition, including a deficit in the recognition of facial emotions and the identification of vocal prosody, is recognized as a part of the cognitive phenotype of Amyotrophic Lateral Sclerosis, with crucial implications for patients' and caregivers' training. However, studies remain scarce and the data acquired must be supported. The evolution of these manifestations during the disease is still poorly understood. In this study the investigators aim to assess the social cognition capacities of patients with Amyotrophic Lateral Sclerosis compared to healthy matched control subjects.
CONDITIONS
Official Title
Social Cognition in Patients With Amyotrophic Lateral Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Education of at least 7 years
- Native language: French
- Signature of informed consent to participate in the study
- Accompanied patient (for ALS patients)
- Patients diagnosed with Amyotrophic Lateral Sclerosis (for ALS patient group)
- People without any pathology (for control group)
You will not qualify if you...
- Simultaneous participation in another interventional protocol with experimental treatment
- Inability to perform cognitive study tests
- Pregnant, lactating or parturient women
- Persons deprived of their liberty by administrative or judicial decision
- Persons under psychiatric care under duress
- Persons subject to legal protection measures
- Persons unable to express their consent
- People not affiliated or not beneficiaries of a social security scheme
- History likely to disturb cognition
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHU Angers
Angers, Angers, France, 49933
Actively Recruiting
Research Team
C
Cassereau Julien
CONTACT
M
Muller Jeanne
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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