Actively Recruiting
Social-cognitive Functioning: Validation of a New Neuropsychological Test
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-03-13
120
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
It is now established that disturbances in social cognition are frequent in neurology and that they contribute to the development of social conduct disorders. Their assessment is therefore essential, particularly in order to propose early and adapted care. However, this assessment remains limited today. A new serious game-type test, REALSoCog, has been developed to address the shortcomings of current tools and to highlight disturbances in social behaviors. The latter are not always observed in consultation although they are often reported by caregivers. The objective of this research is therefore to validate the REALSoCog task in a pathological population (currently being standardized in the general population: CER-U, IRB N°: 00012020-115). The clinical interest of this task will be tested with a group of patients suffering from a neurodegenerative disease (Alzheimer's disease (AD), dementia with Lewy bodies (DCL), fronto-temporal lobar degeneration (FTD)) in order to assess its sensitivity and specificity in the detection of social-cognitive disturbances, and in particular in terms of social behaviors (detection of social behavioral disorders reported in daily life). The objective is also to document the socio-cognitive profiles in the mentioned diseases thanks to a more ecological test, and to better understand the links between socio-cognitive processes on the one hand, and individual characteristics on the other hand (e.g. mood and social participation).
CONDITIONS
Official Title
Social-cognitive Functioning: Validation of a New Neuropsychological Test
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged between 18 and 90 years
- Mini Mental State Examination (MMSE) score greater than or equal to 20
- Patient able to give informed and autonomous consent
- Diagnosis of frontotemporal degeneration, Alzheimer's disease, or Lewy body dementia
- Caregiver over 18 years old
- Caregiver has regular contact with patient at least twice per month
You will not qualify if you...
- Neurological or psychiatric comorbidity
- Significant sensory disorders interfering with the study (e.g., profound deafness, blindness)
- Patient opposes participation in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital de la Pitié-Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
M
Marc VERNY, Pr
CONTACT
P
Pauline NARME
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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