Actively Recruiting
Social Disconnection Study
Led by Yale University · Updated on 2025-03-21
100
Participants Needed
1
Research Sites
247 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research study is to examine the effect of social connectedness on the brain. Study procedures include one Magnetic Resonance Imaging (MRI) or functional Magnetic Resonance Imaging (fMRI) scan, one Positron Emission Tomography (PET) scan, one Magnetic Resonance Spectroscopy (MRS) scan, an electroencephalogram (EEG), and in-person and phone call follow-ups.
CONDITIONS
Official Title
Social Disconnection Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to give written informed consent
- Age 55 or older
- English speaking
You will not qualify if you...
- Cannot have MRI due to claustrophobia, body size, brain changes, or metal in the body including braces
- Women who are pregnant or breastfeeding
- Serious medical or neurological illness affecting safety or study goals
- Pervasive developmental or primary psychotic disorders
- Current severe substance use disorder (except marijuana or nicotine)
- History of significant head injury causing long-term cognitive decline
- Current psychosis or active suicidal/homicidal thoughts
- History of neurological abnormalities like seizure disorder or stroke
- Full scale IQ below 70
- Cannot have PET due to poor vein access
- Prior research radiation exposure exceeding limits within the past year
- Bleeding disorder or use of blood thinners if arterial line needed
- Blood donation within 8 weeks before study start
- REM sleep disorder
- Lifetime brain injury such as TBI, epilepsy, stroke, or TIA
- Electroconvulsive, ketamine, or similar brain therapies in past 6 months
- High risk for stroke based on Framingham Stroke Risk Profile
- Current cancer
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Yale Translational Brain Imaging Program
New Haven, Connecticut, United States, 06510
Actively Recruiting
Research Team
S
Sarah Boster, MA
CONTACT
N
Nicole DellaGioia, MA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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