Actively Recruiting
Social Functioning in Opioid Use Disorder
Led by Medical University of South Carolina · Updated on 2026-04-30
230
Participants Needed
1
Research Sites
170 weeks
Total Duration
On this page
Sponsors
M
Medical University of South Carolina
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treatment outcomes are poorly understood. This study will utilize both data from both patients with OUD and their concerned significant other (CSO) to examine associations between specific social functioning metrics and OUD treatment outcomes. Findings from this study will inform future precision-medicine approaches for people with OUD, a population in significant need of enhanced treatment approaches to combat opioid morbidity and mortality.
CONDITIONS
Official Title
Social Functioning in Opioid Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any sex or gender; any race or ethnicity; aged 18 years or older
- Patient participants must meet DSM-5 diagnostic criteria for current (past 12 months) opioid use disorder
- Patient participants must be on buprenorphine prescribed by their provider for no more than 4 weeks before starting the study
- Patient participants must be receiving treatment at specified clinics in the Charleston area
- Concurrent substance use disorders are allowed if opioids are the primary substance of choice
- Patient participants must identify a concerned significant other who agrees to participate
You will not qualify if you...
- Moderate-to-severe opioid withdrawal as defined by a score of 6521 on the Subjective Opioid Withdrawal Scale
- History or current diagnosis of psychotic or bipolar disorders
- Current suicidal or homicidal thoughts with intent requiring hospitalization
- Concerned significant others with opioid or other substance use disorders except tobacco use disorder
- Severe interpersonal violence between patient and concerned significant other in the past six months
- Pregnancy in patient participants
- Prisoners, institutionalized individuals, and children are not eligible for this study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Medical University of South Carolina
Charleston, South Carolina, United States, 29412
Actively Recruiting
Research Team
A
Amber Anderson, BA
CONTACT
K
Kevin Branson, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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