Actively Recruiting
Sodium Bicarbonate for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma.
Led by Sun Yat-sen University · Updated on 2025-03-03
196
Participants Needed
1
Research Sites
258 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate whether the use of 2.5% sodium bicarbonate mouthwash throughout the entire course of radiotherapy for nasopharyngeal carcinoma reduces the severity of radiation-induced oral mucositis and improves patient adherence to treatment.
CONDITIONS
Official Title
Sodium Bicarbonate for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathologically confirmed nasopharyngeal carcinoma
- No evidence of distant metastasis (M0)
- Scheduled to receive radical radiotherapy
- Karnofsky scale (KPS) > 70
- Age 18-70 years
- Able to perform oral rinsing independently without difficulty swallowing
You will not qualify if you...
- Receiving non-platinum-based concurrent chemotherapy regimens
- Radiation fields including level Ib lymph nodes
- History of pre-existing oral mucosal disorders or recurrent oral ulcers
- Prior radiotherapy treatment
- Severe other illnesses
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China, 510060
Actively Recruiting
Research Team
L
Ling-Long Tang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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