Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT05388032

Sodium Lowering Vascular Effects Trial

Led by Tulane University · Updated on 2024-11-22

256

Participants Needed

1

Research Sites

205 weeks

Total Duration

On this page

Sponsors

T

Tulane University

Lead Sponsor

J

Johns Hopkins University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed mechanistic trial will test the effect of dietary sodium reduction on cardiac and vascular structure and function in those with elevated blood pressure or hypertension. Findings from this study will fill the knowledge gap on the underlying mechanisms of dietary sodium intake on cardiovascular disease risk in addition to blood pressure and could provide further evidence on sodium reduction for the prevention of cardiovascular disease.

CONDITIONS

Official Title

Sodium Lowering Vascular Effects Trial

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men or women aged 40 years or older
  • Elevated blood pressure or hypertension defined as systolic BP ≥120 mmHg and diastolic BP ≥80 mmHg, with or without antihypertensive medications
Not Eligible

You will not qualify if you...

  • Glomerular filtration rate (eGFR) less than 30 or end-stage renal disease
  • History of cardiovascular disease
  • Shift worker or regularly working at night
  • Cancer requiring chemotherapy or radiation treatment in the past two years
  • Current pregnancy, breastfeeding, or plans to become pregnant during the study
  • Consumption of 21 or more alcoholic drinks per week
  • Current participation in another lifestyle intervention or drug trial
  • Residence or planned residence making it difficult to meet trial requirements
  • Other concerns about ability to meet trial requirements as determined by the study coordinator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tulane University Office of Health Research

New Orleans, Louisiana, United States, 70112

Actively Recruiting

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Research Team

M

Marigny Bostock, MA, CHES

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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