Actively Recruiting
Sodium vs Potassium Education to Improve Vascular Health
Led by Florida State University · Updated on 2026-04-23
32
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
Sponsors
F
Florida State University
Lead Sponsor
U
United States Department of Agriculture (USDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy young adults who typically consume more than the recommended amount of sodium. The main questions it aims to answer are: 1. Is it easier for young adults to increase their potassium intake, rather than reduce their sodium intake? 2. Is a self-selected high potassium diet better at improving vascular health compared to a self-selected low sodium diet? Researchers will compare the effectiveness of an education-based intervention centered only on increasing dietary potassium intake against an education-based intervention centered only on reducing dietary sodium intake. Participants will be randomly assigned to receive comprehensive dietary education on adopting either a high-potassium diet or a low-sodium diet. Education will be delivered in four weekly one-on-one sessions. Following the four-week education period, participants will be encouraged to change their diet based on what they have learned. Measures of dietary compliance (urine samples and diet records) and cardiovascular health (blood pressure, endothelial function) will be assessed at two, four, and six months post-education.
CONDITIONS
Official Title
Sodium vs Potassium Education to Improve Vascular Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing and able to attend in-person laboratory visits
- Usual sodium intake of at least 3,000 mg/day for females and 4,000 mg/day for males
- Usual potassium intake of 2,500 mg/day or less for females and 3,000 mg/day or less for males
You will not qualify if you...
- Body Mass Index (BMI) of 35 kg/m2 or higher
- Seated blood pressure of 130/80 mmHg or higher
- Current or past diagnosis of diabetes, kidney disease, cancer, cardiovascular disease, or major cardiovascular events like heart attack or stroke
- Current or recent use of diuretics within the past 6 months
- Elevated LDL cholesterol of 190 mg/dL or higher
- Elevated serum potassium levels above 5.1 mmol/L
- Elevated blood urea nitrogen (BUN) above 22 mg/dL
- Elevated creatinine above 1.2 mg/dL
- Low estimated glomerular filtration rate (eGFR) below 90 mL/min/1.73 m2
- Current or recent use of tobacco, nicotine, or illicit drugs
- Radical hysterectomy or oophorectomy for females
- Pregnant or breastfeeding
- Following a weight-loss diet or planning to gain or lose weight during the study period
AI-Screening
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Trial Site Locations
Total: 1 location
1
Florida State University
Tallahassee, Florida, United States, 32304
Actively Recruiting
Research Team
A
Andrea Lobene, PhD, RD, LD
CONTACT
F
FSU Ann's College
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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