Actively Recruiting
Sodium-rich COndiments Unifying Health and Taste
Led by Singapore Institute of Food and Biotechnology Innovation · Updated on 2026-02-09
32
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to develop an evidence-based classification for sodium-rich condiments (natremic index) based on their CVD-related risks. It is hypothesised that the acute cardiovascular and physiological response (effectively extrapolated to long-term CVD risks) to meals prepared with various sodium-rich condiments can be leveraged upon for the development of such an index that will systematically classify sodium-rich condiments based on the risk they present to cardiovascular health.
CONDITIONS
Official Title
Sodium-rich COndiments Unifying Health and Taste
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 50 and less than 75 years old
- Male or postmenopausal female (self-reported)
- Body weight 50 kg or more
- Systolic blood pressure between 130 and less than 160 mmHg or diastolic blood pressure between 85 and less than 100 mmHg
- Willing and able to follow the intervention protocol
- Ability to identify basic tastes (by taste discrimination test)
- English speaking
You will not qualify if you...
- Taking medications that may affect study outcomes (e.g., for blood pressure or blood thinning) without consultation
- Type 1 or type 2 diabetes mellitus (fasting blood glucose ≥ 7.0 mmol/L or HbA1c ≥ 6.5%)
- Taking dietary supplements that may affect outcomes within one month prior to first visit without consultation
- Obesity (BMI ≥ 27.5 kg/m2)
- History or current diagnosis of hematological, hepatic, renal, gastrointestinal, or other relevant diseases affecting outcomes without consultation
- History of arteriovenous shunt or mastectomy
- Women who are pregnant, lactating, or planning pregnancy
- History or current diagnosis of HIV or tuberculosis
- History of severe vasovagal syncope after blood draw
- Drug abuse within the last 5 years
- Excessive alcohol consumption (more than 2 servings per day)
- Smoking (cigarettes, e-cigarettes, cigars, pipes, vape)
- Engaging in habitual vigorous physical activity
- Allergy or intolerance to intervention foods
- Dislike or unwillingness to consume intervention foods
- Photophobia, especially sensitivity to intense red lights
- Sinus problems affecting taste and smell
- Participation in other clinical studies influencing outcomes
- Being an ASTAR staff member
- Being a study team member or their immediate family member
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Clinical Nutrition Research Centre
Singapore, Singapore, 117599
Actively Recruiting
Research Team
D
Darel Toh, PhD
CONTACT
B
Bhupinder Kaur, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
4
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