Actively Recruiting
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
Led by Harvard Medical School (HMS and HSDM) · Updated on 2024-08-14
40
Participants Needed
1
Research Sites
123 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants. The main questions it aims to answer are: How do different materials (titanium, PEEK, zirconia, and lithium disilicate) affect inflammation around dental implants? What changes occur in inflammation markers in the gum tissue after 3 and 6 months? Researchers will compare the different materials to see which one causes the least amount of inflammation. Participants will: Receive dental implants made from different materials. Have samples of fluid from around their implants collected for analysis at 3 and 6 months. Undergo regular dental check-ups to measure gum health, such as bleeding and pocket depth around the implants.
CONDITIONS
Official Title
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be 18 years or older.
- Participants must be edentulous with at least four missing teeth in the posterior region of the mandible or maxillae.
- Participants must have appropriate oral hygiene and periodontal status of natural teeth, with a pocket depth of 4mm or less and no bleeding.
- Dental implants must be fully integrated with no bone resorption or inflammation after three months of implant placement, confirmed by X-ray and clinical examination.
- Implant placement must be into natural bone without additional procedures such as sinus lift or bone augmentation.
- The procedure must be a standard implantation with no immediate implant placement.
- The height of the gingiva must be at least 3mm or more.
You will not qualify if you...
- Patients with systemic diseases such as malignancy, diabetes, osteoporosis, or rheumatoid arthritis.
- Patients with a history of periodontal treatment.
- Patients who smoke or use tobacco.
- Patients who have received antibiotic treatment within three months prior to implantation.
- Pregnant individuals.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
VIC Clinic
Vilnius, Lithuania, 01362
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
4
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