Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06873685

Soft Tissue Sarcoma: Motor Performance, Robotic Rehabilitation, Nutrition, and Quality of Life

Led by Fondazione Policlinico Universitario Campus Bio-Medico · Updated on 2025-03-21

120

Participants Needed

3

Research Sites

76 weeks

Total Duration

On this page

Sponsors

F

Fondazione Policlinico Universitario Campus Bio-Medico

Lead Sponsor

F

Fondazione Don Carlo Gnocchi Onlus

Collaborating Sponsor

AI-Summary

What this Trial Is About

Soft tissue sarcomas are a group of rare and heterogeneous tumors. Surgery is the mainstay of treatment and microscopic negative margins need to be achieved to improve disease local control. We designed this prospective study to evaluate the main features of motor impairment and the impact of tailored robotic rehabilitation techniques in patients treated for localized soft tissue sarcoma (surgery alone, or surgery + radiation or radiochemotherapy). Specific patients' motor strategies will be quantitatively measured through a biomechanical assessment, including the analysis of joint kinematics, and muscle activity timing patterns. Considering the influence of motor impairment after demolitive surgery, a major interest of this study will be focused on nutrition and Quality of life which will be prospectively evaluated by specific questionnaires at different time points.

CONDITIONS

Official Title

Soft Tissue Sarcoma: Motor Performance, Robotic Rehabilitation, Nutrition, and Quality of Life

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient with primary and localized soft tissue sarcoma eligible for limb-sparing surgery or retroperitoneal multivisceral resection with curative intent
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Recurrent tumors
  • Metastatic disease
  • Candidate for palliative or non-radical surgery
  • Refusal to sign informed consent
  • Pregnant or breastfeeding at the time of screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Fondazione Policlinico Universitario Campus Bio-Medico

Rome, Lazio, Italy, 00128

Actively Recruiting

2

Fondazione Don Carlo Gnocchi ONLUS

Roma, RM, Italy, 00166

Active, Not Recruiting

3

Istituto Nazionale Tumori-IRCCS-Fondazione G.Pascale

Naples, Italy, 80131

Not Yet Recruiting

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Research Team

B

Bruno Vincenzi

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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