Actively Recruiting

Age: 12Years +
All Genders
NCT05942456

Soluble B7-H3 as a Biomarker for Osteosarcoma

Led by Peking University People's Hospital · Updated on 2024-05-14

200

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Increasing data has indicated an association between increased soluble B7-H3 (sB7-H3) levels and unfavorable prognosis in patients with malignancies. However, the level of sB7-H3 and its clinical significance in osteosarcoma are not well known. In this present study, we investigated whether sB7-H3 levels in serum could be as a biomarker for osteosarcoma treatment.

CONDITIONS

Official Title

Soluble B7-H3 as a Biomarker for Osteosarcoma

Who Can Participate

Age: 12Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • High-grade osteosarcoma confirmed by pathology
  • No prior systemic treatment before the first blood draw
  • ECOG performance status 0 or 1 and able to tolerate standard PKUPH-OS-02 neoadjuvant chemotherapy
  • Complete radiographs available for clinical evaluation
Not Eligible

You will not qualify if you...

  • Unable to tolerate blood draws
  • Incomplete medical records in the PKUPH system
  • Unable to tolerate PKUPH-OS-02 neoadjuvant chemotherapy
  • Other conditions deemed unsuitable by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China, 100044

Actively Recruiting

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Research Team

L

Lu Xie, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Soluble B7-H3 as a Biomarker for Osteosarcoma | DecenTrialz