Actively Recruiting
Sore Throat After Open Neck Elective Surgery
Led by Saint Petersburg State University, Russia · Updated on 2026-04-13
764
Participants Needed
1
Research Sites
84 weeks
Total Duration
On this page
Sponsors
S
Saint Petersburg State University, Russia
Lead Sponsor
S
Smooth Drug Development
Collaborating Sponsor
AI-Summary
What this Trial Is About
This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough following thyroid or parathyroid surgery with neuromonitoring. A total of 764 adult patients undergoing elective neck surgery at Saint-Petersburg State University Hospital will be enrolled and randomly assigned to receive either a hydrocortisone-coated or lidocaine-coated endotracheal tube. Outcomes will be assessed upon awakening from anesthesia, at 24 hours, and again at 3 days postoperatively. The findings may contribute to improving postoperative comfort and recovery for patients undergoing similar surgical procedures.
CONDITIONS
Official Title
Sore Throat After Open Neck Elective Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for elective open surgery on the thyroid/parathyroid glands with intraoperative neuromonitoring.
- Age ≥18 years.
- Willing and able to provide voluntary informed consent for participation in the study.
You will not qualify if you...
- Pregnancy (for women of childbearing potential).
- Known allergy to hydrocortisone or lidocaine.
- Refusal to participate in the study.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Saint Petersburg State University Hospital
Saint Petersburg, Russia
Actively Recruiting
Research Team
S
Sergey M. Efremov, D. Med. Sc.
CONTACT
A
Alexey Y. Kulikov, Ph. D. (Med.)
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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