Actively Recruiting

Phase Not Applicable
Age: 60Years - 90Years
All Genders
NCT06891573

South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention

Led by Seong Hye Choi, MD · Updated on 2025-11-20

40

Participants Needed

3

Research Sites

46 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this feasibility randomized controlled trial is to investigate the applicability of software that aims to improve symptoms of frailty by implementing customized interventions such as physical exercise and cognitive training implemented through a mobile app for 16 weeks for patients diagnosed with frailty or prefrailty. The primary outcomes are adherence, retention rates, and recruitment rates. Participants will participate in customized interventions including physical exercise, cognitive training, nutritional guidance, and management of disease related to frailty for 16 weeks.

CONDITIONS

Official Title

South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention

Who Can Participate

Age: 60Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 60 and 90 years
  • Living in the community
  • Modified Fried frailty phenotype score of 1 point or higher
  • Korean Mini-Mental State Examination-2 z-score of -1.5 or higher
  • Ability to read and write
  • Able to use a mobile app independently or with help
  • Having a reliable informant to provide health information
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Major psychiatric illnesses such as major depressive disorders
  • Dementia
  • Other neurodegenerative diseases like Parkinson's disease
  • Cancer diagnosed within the past five years
  • Cardiac stent placement or revascularization within the last year
  • Serious or unstable symptomatic cardiovascular disease
  • Other serious or unstable medical conditions such as acute or severe asthma, active gastric ulcer, severe liver disease, or severe kidney disease
  • Severe vision or hearing loss, or communication disabilities
  • Significant lab abnormalities that could cause cognitive impairment
  • Any condition preventing cooperation as judged by the study physician
  • Unable to safely participate in the exercise program
  • Currently enrolled in another intervention trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Inha University Hospital

Incheon, South Korea, 22332

Actively Recruiting

2

Ewha Womans University Seoul hospital

Seoul, South Korea

Not Yet Recruiting

3

Ajou University Hospital

Suwon, South Korea

Not Yet Recruiting

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Research Team

S

Seong Hye Choi, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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