Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06053320

Spatial-Motor Stroke-Rehab Study

Led by Emory University · Updated on 2025-10-16

65

Participants Needed

3

Research Sites

150 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

CONDITIONS

Official Title

Spatial-Motor Stroke-Rehab Study

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 30 years who are healthy without physical or neurological disabilities
  • Adults aged 45 to 90 years who are healthy without physical or neurological disabilities
  • Adults aged 40 to 90 years with right hemisphere stroke at least 3 months prior
  • Presence of aiming spatial neglect
  • Ability to walk more than 10 meters with or without assistive devices
  • Unilateral left-sided hemiparesis with arm strength grade 4/5 or less on the Medical Research Council Scale
  • Ability to follow 3-stage commands and provide informed consent
Not Eligible

You will not qualify if you...

  • History or signs of orthopedic or physical disability
  • History or signs of neurological disorders
  • Pregnancy (female participants)
  • Uncontrolled hypertension
  • Presence of cardiac pacemaker or other implanted electronic device
  • Skin conditions preventing electrical stimulation setup
  • Impaired sensation in the left upper limb
  • Bruises or cuts at electrode placement sites
  • Participation in other rehabilitation or investigational studies
  • Severe uncontrolled medical conditions such as cardiovascular disease, rheumatoid arthritis, active cancer, renal disease, or epilepsy
  • Contraindications to transcranial magnetic stimulation such as metal implants or medications increasing cortical excitability
  • History of multiple strokes or brainstem strokes (stroke group)
  • Cerebellar disorders (stroke group)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Emory Rehabilitation Hospital

Atlanta, Georgia, United States, 30322

Actively Recruiting

2

Emory University Hospital (EUH)

Atlanta, Georgia, United States, 30322

Actively Recruiting

3

Executive Park

Atlanta, Georgia, United States, 30329

Actively Recruiting

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Research Team

F

Fisayo Aloba, PT, DPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

3

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