Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT06968689

Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain

Led by The University of Texas Health Science Center, Houston · Updated on 2026-03-02

60

Participants Needed

1

Research Sites

143 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center, Houston

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)

CONDITIONS

Official Title

Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Meet the MRI / EEG screening criteria
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Current or history of major medical, neurological, or psychiatric illness based on self-report
  • History of cardiac, respiratory, or nervous system disease that could increase risk, such as asthma or claustrophobia
  • History of head trauma
  • Pregnant or lactating
  • Any contraindications to MRI scanning, including pacemaker, metal implants, claustrophobia, pregnancy, or inability to lie still
  • Conditions that make participation difficult, such as paralysis or severe psychological problems
  • Active substance abuse disorders based on self-report

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

Loading map...

Research Team

W

Wen Li, PhD

CONTACT

J

Jada Malveaux

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

6

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain | DecenTrialz