Actively Recruiting
Speckle Tracking Echocardiography for the Prediction of Weaning Failure
Led by Assistance Publique Hopitaux De Marseille · Updated on 2026-02-12
110
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Deciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not accurate. Recent studies suggest that isolated sonographic assessment of the respiratory and cardiac function (ie diastolic function and filling pressure), in mechanically ventilated patients may assist in identifying patients at risk of weaning failure. Recently, the association of conventional echocardiography and lung ultrasound showed promising results for the prediction of post extubation distress. Speckle Tracking is an emerging tool in intensive care medicine that has never been investiguated for the prediction of weaning failure. It could early detects diastolic dysfunction and and elevated filling pressure. Of more, speckle tracking is known to be less operator dependant. The main objective of our study is to evaluate the diagnosis accuracy of speckle tracking echocardiography performed during a weaning trial to predict weaning failure. The secondary objectives are to assess the diagnosis accuracy of combined heart and lung ultrasound to predict weaning failure.
CONDITIONS
Official Title
Speckle Tracking Echocardiography for the Prediction of Weaning Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients hospitalized in intensive care unit under mechanical fulfilling the criteria of ventilation weaning trial.
You will not qualify if you...
- Under 18 years old.
- Pregnancy.
- Non sinusal cardiac rhythm.
- Neuro Myopathy.
- Tracheotomy.
- Lack of echogenicity to perform at least a four chamber apical view.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Assistance Publique Hôpitaux de Marseille
Marseille, France, 13015
Actively Recruiting
Research Team
L
Laurent ZIELESKIEWICZ
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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