Actively Recruiting
SPECT-CT vs MRI for the Diagnosis of Osteoarthritis in the Foot and Ankle
Led by Martini Hospital Groningen · Updated on 2026-02-27
132
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The diagnose of symptomatic osteoarthritis in the ankle, mid- and hind foot remains challenging. There is no gold standard for the work-up and various hospitals use different protocols. Current literature shows a promising role for SPECT-CT imaging in ankle, hind- and midfoot OA. In a previous study investigating the role of SPECT-CT in a reproducible group we have observed a change in diagnosis in 53% when SPECT-CT data was added to the data of conventional workup alone. In 26% of patients addition of SPECT-CT data resulted in change of the original treatment plan. To our knowledge no prospective studies are available on this subject for both SPECT-CT and MRI. In our clinic both SPECT-CT and MRI are used in the work-up for patients with ankle, hind- and midfoot pain. Although we experience good result with SPECT-CT, MRI might be able to detect symptomatic OA as well. Moreover MRI provide more information about soft tissue and is less harmful for the patient in comparison to SPECT-CT. The aim of this study is to determine the diagnostic performance of SPECT-CT and MRI when used routinely in patients with symptomatic OA of the ankle, hind- and midfoot.
CONDITIONS
Official Title
SPECT-CT vs MRI for the Diagnosis of Osteoarthritis in the Foot and Ankle
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suspected symptomatic ankle, hind- or midfoot OA
- Informed consent
- Age ≥ 18 years
- Average NRS ≥4 over the past week.
You will not qualify if you...
- Contraindication for surgery
- Contraindication for SPECT-CT or MRI
- Contraindication for intra-articular injections
- Isolated forefoot pathology
- Fracture, ligamentous or tendon injury of the ankle, hind- and/or midfoot trauma within one year before presentation
- History of neurological disease
- History of foot and/or ankle surgery (affected side)
- Inability to read and understand the written information
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Martini Hospital
Groningen, Netherlands, 9728 NT
Actively Recruiting
Research Team
A
Arthur van Hasselt, MD
CONTACT
A
Astrid de Vries, dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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