Predictive Performance of SPECT/CT Bone Scan Quantification Before Lumbar Arthrodesis Surgery for Chronic Low Back Pain

What this Trial Is About

Researchers are investigating whether SPECT/CT bone scan measurements using a CZT solid state camera before surgery can predict good outcomes after lumbar arthrodesis surgery for chronic low back pain. This condition, often resistant to medical treatment, involves fusing adjacent vertebrae to relieve pain and improve function. The study explores if a specific bone scan value, SUVmax, correlates with improvements measured by the Oswestry Disability Index (ODI) and numerical pain scale after surgery. Participants who will undergo lumbar arthrodesis surgery performed by experienced neurosurgeons will receive a bone scan before their operation. The surgery targets up to two spinal levels using standard techniques. Patients will complete pain and disability questionnaires before and after surgery to assess changes. The bone scan results will be analyzed to see if they can identify patients who respond well to the surgery. During the study, participants will be monitored through questionnaires assessing pain and disability over 24 months. Researchers will evaluate the correlation between the bone scan SUVmax value and surgical outcomes based on the ODI. The study excludes patients with neuropathic pain or other spine conditions and includes safety monitoring for radiopharmaceutical allergies and ability to remain still during scans. This research aims to improve preoperative selection of patients likely to benefit from lumbar fusion surgery.

SPECT/CT Bone Scan Quantification Surgery