Actively Recruiting
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
Led by Emory University · Updated on 2026-03-04
25
Participants Needed
3
Research Sites
616 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This trial studies how well spectroscopic magnetic resonance imaging (MRI) guided proton therapy works in assessing metabolic change in pediatric patients with brain tumors. The non-invasive imaging, such as spectroscopic MRI may help to map the differences in tumor metabolism compared to healthy tissue without injection of any contrast agent.
CONDITIONS
Official Title
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with high-grade glioma (WHO grade 3-4); those with radiographic diagnosis may enroll before pathology confirmation
- Primary tumor located in the supratentorial brain
- Recommended to receive definitive radiation therapy
- Able to undergo MRI scans
- Both males and females of all races and ethnic groups are eligible
You will not qualify if you...
- Presence of pacemakers, non-titanium aneurysm clips, neurostimulators, cochlear implants, non-titanium metal in eye structures, or other implants unsafe for MRI
- Significant medical illnesses preventing safe MRI scan
- Pathology showing low-grade glioma or benign/non-invasive brain tumor
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Emory Proton Therapy Center
Atlanta, Georgia, United States, 30308
Actively Recruiting
2
Children's Healthcare of Atlanta - Scottish Rite
Atlanta, Georgia, United States, 30322
Not Yet Recruiting
3
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Actively Recruiting
Research Team
B
Bree Eaton, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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