Actively Recruiting
Neural Processing of Speech Signals in Children Who Stutter
Led by University of Pittsburgh · Updated on 2025-09-15
600
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
U
University of Michigan
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating how speech and language are processed in the brains of children, focusing on differences between those who stutter and those who do not. This study aims to improve understanding of the neural mechanisms behind speech sound encoding and how these processes change with different task demands, using advanced brain imaging and computational modeling methods. Participants will undergo a range of speech sound tests, EEG tasks measuring brain responses to speech signals, and functional MRI scans to explore brain activity during speech tasks. These assessments include listening and identifying syllables, as well as comprehending continuous speech, both in quiet and noisy settings. The study also involves structural brain scans and uses computational techniques to analyze brain activity and speech processing. Children in the study will complete standardized speech, language, and cognitive tests administered by trained professionals. They will wear scalp electrodes for EEG recording and undergo MRI scanning with safety screenings for metal objects. Researchers will measure multiple brain responses and activations related to speech processing during single sessions lasting up to two hours. The entire participation involves behavioral assessments, brain recordings, and imaging to examine speech sound identification and neural activity.
CONDITIONS
Brief Title
Speech Signals in Stuttering
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Speaks English as primary language
- Language abilities within the typical range
- Cognitive abilities within the typical range
- No contraindications for MRI
- Presence of developmental stuttering (onset in childhood) for children who stutter
- No history of other communication disorder for children who stutter
- No family history of stuttering for children who do not stutter
- No history of other communication disorders for children who do not stutter (e.g., hearing impairment, language impairment, cognitive impairment/injury)
You will not qualify if you...
- Taking medication that alters neural function
- Cognitive skills below the typical range
- Major medical illness
- Not a fluent speaker of English
- Pregnant or possibly pregnant
- Metal implants in your body (including pacemakers, neurostimulators, or other metal objects)
- Shrapnel injuries
- Ocular foreign bodies (e.g., metal shavings)
- Metal piercings that cannot be removed for the scan
- Tattoos containing iron or metal pigments
- Prone to claustrophobia
- For fMRI, head circumference greater than 60cm or weight over 300 pounds due to scanner size limits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete speech sound tasks of varying difficulty including behavioral tests, EEG measurements, and MRI scans to evaluate neural processing of speech signals.
Up to 1 to 3 sessions lasting up to 2 hours each
Trial Site Locations
Total: 2 locations
1
University of Michigan
Ann Arbor, Michigan, United States, 48105
Not Yet Recruiting
2
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
B
Brittany Coleman, MS, CCC-SLP
A
Ashley Parker, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here