Actively Recruiting

Phase Not Applicable
Age: 5Years - 17Years
All Genders
Healthy Volunteers
ID05668923

Neural Processing of Speech Signals in Children Who Stutter

Led by University of Pittsburgh · Updated on 2025-09-15

600

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

U

University of Michigan

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating how speech and language are processed in the brains of children, focusing on differences between those who stutter and those who do not. This study aims to improve understanding of the neural mechanisms behind speech sound encoding and how these processes change with different task demands, using advanced brain imaging and computational modeling methods. Participants will undergo a range of speech sound tests, EEG tasks measuring brain responses to speech signals, and functional MRI scans to explore brain activity during speech tasks. These assessments include listening and identifying syllables, as well as comprehending continuous speech, both in quiet and noisy settings. The study also involves structural brain scans and uses computational techniques to analyze brain activity and speech processing. Children in the study will complete standardized speech, language, and cognitive tests administered by trained professionals. They will wear scalp electrodes for EEG recording and undergo MRI scanning with safety screenings for metal objects. Researchers will measure multiple brain responses and activations related to speech processing during single sessions lasting up to two hours. The entire participation involves behavioral assessments, brain recordings, and imaging to examine speech sound identification and neural activity.

CONDITIONS

Brief Title

Speech Signals in Stuttering

Who Can Participate

Age: 5Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Speaks English as primary language
  • Language abilities within the typical range
  • Cognitive abilities within the typical range
  • No contraindications for MRI
  • Presence of developmental stuttering (onset in childhood) for children who stutter
  • No history of other communication disorder for children who stutter
  • No family history of stuttering for children who do not stutter
  • No history of other communication disorders for children who do not stutter (e.g., hearing impairment, language impairment, cognitive impairment/injury)
Not Eligible

You will not qualify if you...

  • Taking medication that alters neural function
  • Cognitive skills below the typical range
  • Major medical illness
  • Not a fluent speaker of English
  • Pregnant or possibly pregnant
  • Metal implants in your body (including pacemakers, neurostimulators, or other metal objects)
  • Shrapnel injuries
  • Ocular foreign bodies (e.g., metal shavings)
  • Metal piercings that cannot be removed for the scan
  • Tattoos containing iron or metal pigments
  • Prone to claustrophobia
  • For fMRI, head circumference greater than 60cm or weight over 300 pounds due to scanner size limits

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Behavioral, Electrophysiological, and Imaging Assessment

Duration - 1 day

Participants complete speech sound tasks of varying difficulty including behavioral tests, EEG measurements, and MRI scans to evaluate neural processing of speech signals.

Up to 1 to 3 sessions lasting up to 2 hours each

Trial Site Locations

Total: 2 locations

1

University of Michigan

Ann Arbor, Michigan, United States, 48105

Not Yet Recruiting

2

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

B

Brittany Coleman, MS, CCC-SLP

A

Ashley Parker, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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