Actively Recruiting
SPG Pulsed Radiofrequency for Chronic Cluster Headache
Led by Beijing Tiantan Hospital · Updated on 2025-01-27
108
Participants Needed
1
Research Sites
309 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cluster headache (CH) is a devastating disorder characterized by ipsilateral headache and associated trigeminal autonomic symptoms, with a yearly prevalence of 0.1%. There is a huge clinically unmet demand for an effective therapeutic method for CH. Previous evidences indicate that pulse radiofrequency (PRF) targeting the sphenopalatine ganglion (SPG) is a safe, minimally invasive, effective treatment for CH. This randomized, controlled trial aimed to establish the safety and efficacy of SPG PRF for patients with chronic CH.
CONDITIONS
Official Title
SPG Pulsed Radiofrequency for Chronic Cluster Headache
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic cluster headache
- At least four attacks per week
- Minimum age of 18 years
- Non-response to verapamil and lithium treatment in the past, intolerance, or contraindication to verapamil and lithium, along with non-response, intolerance, or contraindication to topiramate, or gabapentin
You will not qualify if you...
- Pregnancy or breastfeeding
- Presence of cardiac pacemaker or other neuromodulatory devices
- Psychiatric and cognitive disorders
- Serious drug habituation or overuse of acute-headache medication
- History of stroke or intracranial aneurysm, or at risk for serious or acute cardiovascular events
- Infection at the puncture site
- Previous history of invasive treatments such as sphenopalatine ganglion radiofrequency thermocoagulation and chemical destruction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fang Luo
Beijing, Beijing Municipality, China, 100070
Actively Recruiting
Research Team
F
Fang Luo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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