Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04819737

Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences

Led by University Hospital, Basel, Switzerland · Updated on 2026-03-05

10

Participants Needed

1

Research Sites

280 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Basel, Switzerland

Lead Sponsor

F

Freie Akademische Gesellschaft Basel

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.

CONDITIONS

Official Title

Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of multiple sclerosis according to established international criteria
  • Steroid-free period of more than 4 weeks
  • Participation in the Swiss MS Cohort (SMSC) study
Not Eligible

You will not qualify if you...

  • History of severe neurological, internal, or psychiatric diseases affecting the spinal cord
  • Presence of paramagnetic or superparamagnetic foreign objects in the body near the spinal cord
  • Having a pacemaker
  • Claustrophobia
  • Pregnancy or lactation
  • Known allergy to gadolinium-based contrast media

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Basel, Department of Neurology

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

K

Katrin Parmar, PD Dr. med.

CONTACT

C

Charidimos Tsagkas, Dr. med.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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