Actively Recruiting

Phase Not Applicable
Age: 50Years - 85Years
All Genders
NCT05527145

Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial

Led by University of Roma La Sapienza · Updated on 2024-02-12

200

Participants Needed

1

Research Sites

95 weeks

Total Duration

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AI-Summary

What this Trial Is About

Symptomatic lumbar spinal stenosis is the most common indication for spinal surgery. However, more than one-third of the patients undergoing surgery for lumbar stenosis report dissatisfaction with the results. On the other hand, conservative treatment has shown positive results in some cases. This trial will compare the outcomes of surgical versus non-surgical treatment for lumbar stenosis.

CONDITIONS

Official Title

Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial

Who Can Participate

Age: 50Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 to 85 years
  • Clinical symptoms of lumbar spinal stenosis with leg pain (Numeric Rating Scale 653)
  • MRI confirming lumbar spinal stenosis at 1 to 3 levels with dural sac area 6475 mm2 or severe stenosis by Schizas's classification
  • Oral and written informed consent given to participate
Not Eligible

You will not qualify if you...

  • Degenerative spinal deformity with Cobb angle greater than 20 degrees
  • Symptomatic osteoarthritis in lower limbs limiting function
  • Arterial insufficiency causing intermittent claudication
  • Prior lumbar surgery except for disc hernia
  • Spine conditions like ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis, spinal infections, malignancy, or neurological diseases
  • Heart or lung disease posing significant surgical risk or preventing participation in non-surgical treatment (ASA score greater than 3)
  • Polyneuropathies
  • Psychological conditions such as drug addiction or dementia that prevent trial participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sapienza University of Rome, Policlinico Umberto I Hospital

Rome, Italy

Actively Recruiting

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Research Team

A

Alessandro napoli, md, phd

CONTACT

S

silvia ciotti

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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