Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06743607

Spinal Stimulation for Upper Extremity Recovery in the Home

Led by Craig Hospital · Updated on 2026-03-31

46

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

Sponsors

C

Craig Hospital

Lead Sponsor

N

National Institute on Disability, Independent Living, and Rehabilitation Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to evaluate the safety, feasibility, and tolerability of non-invasive spinal stimulation used in the home and/or community in combination with a functional home exercise program for the upper extremities (arm/hand function) as well as their combined impacts on changes in upper extremity function. The expected duration of participation in this study is about 31-33 hours over a 13-25-week period. Enrollees in this study will be randomly assigned to one of two groups: 1) upper extremity functional task-specific training combined with non-invasive transcutaneous spinal stimulation, or 2) waitlist control, which involves the same intervention, but with a 12-week delayed start. Participants complete initial testing (one time if in group one and three times \[at weeks 0, 8, and 12\] if in group two), 24 1-hour training sessions (2x/week in home with caregiver/companion support and 1x/week with research team in person or via video conference for 8 weeks), a post-treatment evaluation, and a final evaluation (4 weeks after post-treatment).

CONDITIONS

Official Title

Spinal Stimulation for Upper Extremity Recovery in the Home

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • History of traumatic spinal cord injury
  • Less than 12 months post spinal cord injury
  • Spinal cord injury level between C1 and C8
  • Injury classified as AIS B-D
  • Have passive range of motion within functional limits at wrists, shoulders, and elbows
  • Have caregiver support to attend three in-person sessions and ongoing home training
  • Caregiver qualified to assist with safe use of transcutaneous spinal stimulation
  • Able to complete in-person training sessions and return for assessments
  • No complicating physical or cognitive conditions preventing safe electrical stimulation
  • Stable dose of prescribed anti-spasticity medications for at least four weeks prior to starting
  • Agree to comply with device instructions, protocol visits, and device return
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Unstable chronic cardiac or respiratory complaints
  • Recent fracture, contractures, or skin pressure injuries interfering with intervention
  • Botox injections to upper extremities, neck, or hands within last three months
  • Pregnant, planning pregnancy, or currently breastfeeding
  • Breakdown in skin area contacting electrodes
  • Prior nerve or tendon transfer procedure for upper extremities
  • Participating in another drug or device trial that may interfere
  • Have implanted pacemaker, spinal cord stimulator, ventriculoperitoneal shunt, deep brain stimulator, or intrathecal pump
  • Study deemed unsafe or inappropriate for participant by investigators

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Craig Hospital

Englewood, Colorado, United States, 80113

Actively Recruiting

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Research Team

C

Candy Tefertiller, PT, DPT, PhD, NCS

CONTACT

B

Bria Mellick, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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