Actively Recruiting
The Spine Phenome Project
Led by Ohio State University · Updated on 2026-03-27
10500
Participants Needed
1
Research Sites
523 weeks
Total Duration
On this page
Sponsors
O
Ohio State University
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational trial is to compare the health history and motion capabilities of participants with low back pain disorders to participants with healthy spines. The main question\[s\] it aims to answer are to: 1. Primary outcomes of this research effort include composite measures that differentiate between control and patient populations, predict injury or reinjury risk, identify low back and neck pain patient phenotypes, and evaluate treatment effectiveness. 2. Secondary outcomes of this research effort include an assessment of wearable motion sensor accuracy, characterization of motion assessment utility, biopsychosocial profiling of control and low back and neck pain patient populations, and differentiation of sincere and insincere motion assessment efforts. Participants will complete questionnaires and wear a motion monitor that will assess your back and/or neck. This session will be approximately 40-70 minutes. The research team will follow up with participants at 3 month, 6 months, 1 year, 2 years, 5 years to complete a short series of questionnaires and a motion assessment test.
CONDITIONS
Official Title
The Spine Phenome Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 and older
- Able to stand for at least 10 minutes (20 minutes for controls)
- Able to speak, read, and understand English
- Currently seeking medical consult with primary complaint of low back pain (for low back pain patients)
- Currently seeking medical consult with primary complaint of neck pain (for neck pain patients)
- Able to stand for 20 minutes (for control participants)
You will not qualify if you...
- Known pregnancy
- Currently seeing or planning to see a medical provider for low back or neck pain (controls only)
- History of chronic low back or neck pain lasting longer than 3 months (controls only)
- Blind or severe uncorrected vision problems preventing reading a tablet or laptop screen
- Deaf or hearing problems preventing hearing verbal instructions
- Actively being treated for concussion
- Known severe spinal deformity requiring medical treatment (e.g. scoliosis)
- Diagnosed with severe vertigo, fainting, narcolepsy, or balance disorders with high fall risk
- Any known fractures within the last 3 months that interfere with motion assessment
- History of spine fracture
- Current condition requiring spine immobilization or bracing
- History of spine surgery (e.g. fusion, micro-discectomy, artificial disc replacement)
- History of brain or spine cancer
- Current or recent (last 90 days) cancer treatment with chemotherapy or radiation
- Known severe osteoporosis requiring treatment and physical restrictions
- Current open wounds or medical device entry points where harnesses are placed
- Current osteomyelitis or spine infection
- Current low back or neck pain due to traumatic injury in last 3 months or spine instability
- Spinal fusion across 4 or more lumbar disc levels (low back pain patients)
- Spinal fusion across 4 or more cervical disc levels or occipital-cervical fusion (neck pain patients)
- Known unstable spondylolisthesis
- Any other reason deemed unsafe by physician, researcher, or participant
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
L
Lindsay Hanes, BS, CCRC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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