Actively Recruiting

Age: 18Years - 99Years
All Genders
ID02241265

Spirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma

Led by University of Oklahoma · Updated on 2025-02-10

20

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate spirometry results in patients with severe asthma who have undergone bronchial thermoplasty. The study is retrospective and will review existing medical records from two medical centers to analyze lung function changes after the procedure. The main goal is to assess improvements in lung function, specifically in forced expiratory volume (FEV1) and forced vital capacity (FVC), one year after treatment. The study focuses on patients who have completed the bronchial thermoplasty procedure, which involves three separate sessions following recommended protocols. Data collected will include age, height, sex, weight, medical and smoking history, as well as spirometric measurements taken before and after the thermoplasty and bronchodilator use. The data comes from records at OU Medical Center and St. Francis Hospital. Participants in this study will not be actively enrolled since it is a retrospective review. Researchers will analyze available spirometry data and other clinical information from past patients. The primary outcome measured is the change in prebronchodilator FEV1 and FVC one year after thermoplasty. Secondary outcomes include changes in postbronchodilator lung function and responsiveness to bronchodilators. No new treatments or visits are required as all data is collected from past records.

CONDITIONS

Brief Title

Spirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years of age
  • Diagnosed with severe asthma
  • Decreased forced expiratory volume in 1 second (FEV1)
Not Eligible

You will not qualify if you...

  • Under 18 years of age

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Long-term Monitoring

Duration - Data collected up to 1 year after bronchial thermoplasty

Participants who underwent bronchial thermoplasty in the past have their spirometric data collected and evaluated to assess lung function changes over time.

Trial Site Locations

Total: 1 location

1

OUHSC

Oklahoma City, Oklahoma, United States, 73104

Actively Recruiting

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Research Team

B

Brent Brown, MD

C

Clinical Trials Manager

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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