Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06995534

Splinting vs Exercise in De Quervain's Tenosynovitis

Led by Konya Beyhekim Training and Research Hospital · Updated on 2026-03-24

40

Participants Needed

1

Research Sites

48 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

De Quervain's disease is a painful tenosynovitis of the abductor pollicis longus and extensor pollicis brevis muscle tendons located in the first dorsal compartment. The primary treatment for De Quervain's disease is conservative; surgical intervention is rarely required. Currently, there is no standardized treatment protocol supported by strong, up-to-date evidence. The aim of this study is to compare the effectiveness of a static hand-wrist resting splint and exercise therapy in the conservative treatment of De Quervain's tenosynovitis. Patients will be evaluated in terms of pain levels, functional/symptom status, hand-finger strength, pressure pain threshold (PPT), tendon cross-sectional area measured by ultrasound, and the presence of effusion findings (semiquantitative; 0-3), and patient satisfaction.

CONDITIONS

Official Title

Splinting vs Exercise in De Quervain's Tenosynovitis

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged between 18 and 65 years
  • Wrist pain and tenderness for less than 3 months
  • Clinical diagnosis of acute or subacute De Quervain's tenosynovitis
  • Visual Analog Scale (VAS) pain score of 3 or higher
Not Eligible

You will not qualify if you...

  • History of trauma
  • Wrist fractures
  • Local infections
  • Rheumatologic diseases like rheumatoid arthritis or psoriatic arthritis
  • Symptomatic hand osteoarthritis
  • Continuous use of NSAIDs or corticosteroids
  • Physical therapy for hand or wrist within the past 3 months
  • Corticosteroid injection into hand or wrist within the past 3 months
  • Significant neurological disorders such as upper motor neuron disease
  • Uncontrolled systemic diseases including diabetes, heart failure, kidney or liver failure
  • Major psychiatric disorders
  • Communication difficulties

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Konya Beyhekim Training and Research Hospital

Konya, Turkey (Türkiye)

Actively Recruiting

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Research Team

E

Eda Ünal Madıoğlu(MD)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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