Unidirectional Vertical Vestibuloocular Reflex Adaptation in Humans Using 1D and 2D Scenes.
Christopher J Todd, Michael C Schubert, Carlo N Rinaudo...
https://pubmed.ncbi.nlm.nih.gov/36075099Actively Recruiting
Led by Johns Hopkins University · Updated on 2025-11-10
48
Participants Needed
2
Research Sites
N/A
Total Duration
J
Johns Hopkins University
Lead Sponsor
N
National Aeronautics and Space Administration (NASA)
Collaborating Sponsor
Researchers are evaluating a self-administered rehabilitation tool designed to help reduce motion sickness and improve balance recovery after centrifugation or surgery affecting the vestibular nerve. This study involves people with vestibular disorders, including those who have had unilateral vestibular schwannoma surgery, as well as healthy individuals with characteristics similar to astronauts. The goal is to assess how guided head movements affect symptoms and recovery. Participants use a device called SWAN that guides sinusoidal head rotations along three axes (yaw, pitch, and roll) for a total of 15 minutes per session. The device encourages users to adjust the movement amplitude based on their level of motion sickness, ranging from none to vomiting. Some participants receive traditional vestibular physical therapy exercises, while others use the automated SWAN method. Healthy controls may receive the SWAN method after motion sickness or no treatment, depending on group assignment. During the study, participants will be monitored daily for up to four weeks. Assessments include motion sickness intensity, eye and head movement measures via video-oculography, heart rate, balance tests with and without head motion, walking speed and endurance, and activity levels. These evaluations help researchers understand changes in vestibular reflexes and overall function. Safety and adherence are tracked throughout the study period.
CONDITIONS
StableEyes With Active Neurofeedback
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Daily for up to 4 weeks
Participants receive either traditional vestibular physical therapy exercises or use the SWAN device for guided vestibular rehabilitation to help reduce motion sickness and improve vestibular function.
Daily visits or assessments for up to 4 weeks
Total: 2 locations
1
Johns Hopkins University
Baltimore, Maryland, United States, 21287
Actively Recruiting
2
Naval Medical Research Unit
Dayton, Ohio, United States, 45433
Enrolling by Invitation
M
Michael Schubert, PhD
M
Matthew Stewart, MD PhD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Christopher J Todd, Michael C Schubert, Carlo N Rinaudo...
https://pubmed.ncbi.nlm.nih.gov/36075099