Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT07228221

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

Led by Jonathon Myers · Updated on 2025-11-14

20

Participants Needed

1

Research Sites

312 weeks

Total Duration

On this page

Sponsors

J

Jonathon Myers

Lead Sponsor

G

Glaukos Corporation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Investigators will investigate the efficacy of combining the standalone iStent infinite and iDose that are minimally invasive surgical and drug depot options are a safe and effective alternative to filtering surgery for intraocuar pressure reduction in patients with medically uncontrolled open angle glaucoma.

CONDITIONS

Official Title

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Moderate to severe open angle glaucoma including primary open angle glaucoma, pigmentary glaucoma, and pseudoexfoliation glaucoma
  • Open angle configuration with Shaffer grade 3 or higher and normal angle anatomy
  • Visual acuity of hand motion or better
  • Visual field mean deviation of -6 dB or worse
  • Failed medical therapy and/or laser treatment
  • Incisional glaucoma surgery planned as next treatment
  • Phakic or pseudophakic eye status
Not Eligible

You will not qualify if you...

  • Traumatic, uveitic, neovascular, or angle closure glaucoma
  • Previous incisional glaucoma surgery
  • History of argon laser trabeculoplasty; iridotomy, selective laser trabeculoplasty, or micropulse laser trabeculoplasty within the past 90 days
  • Active ocular inflammation or edema
  • Clinically significant corneal dystrophy
  • Corneal or other eye pathology that prevents accurate Goldmann applanation tonometry

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wills Eye Hosital Glaucoma Dept.

Philadelphia, Pennsylvania, United States, 19107

Actively Recruiting

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Research Team

M

Meskerem Divers

CONTACT

J

Jeanne L Molineaux, COA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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