Actively Recruiting
Standardized Fecal Microbiota Transplantation for Crohn&Apos;s Diseases
Led by The Second Hospital of Nanjing Medical University · Updated on 2024-11-29
800
Participants Needed
2
Research Sites
669 weeks
Total Duration
On this page
Sponsors
T
The Second Hospital of Nanjing Medical University
Lead Sponsor
T
The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body's metabolism. Evidence from animal and human studies strongly supports the link between intestinal bacteria and inflammatory bowel diseases (IBD). Dozens of studies reported its efficacy in treatment of severe Clostridium difficile colitis. Preliminary studies using fecal microbiota transplantation (FMT) for Ulcerative Colitis (UC), Crohn's diseases (CD), irritable bowel syndrome (IBS) and constipation have also met with some success. However, the results on CD is very limited. This marks the initial step in exploring the potential efficacy of fecal bacteriotherapy for CD. The investigators aim to evaluate the effectiveness, durability, and safety of FMT in a cohort of at least 500 patients with CD over a ten-year period
CONDITIONS
Official Title
Standardized Fecal Microbiota Transplantation for Crohn&Apos;s Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of Crohn's disease confirmed after at least three months of follow-up
- Willingness to undergo fecal microbiota transplantation (FMT)
You will not qualify if you...
- Presence of serious conditions such as malignant neoplasms, cardiopulmonary failure, or severe liver or kidney disease that make participation unsuitable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University
Huai'an, Jiangsu, China, 223000
Actively Recruiting
2
Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210011
Actively Recruiting
Research Team
F
Faming Zhang, MD, PhD
CONTACT
H
Huijie Zhang, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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