Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
Healthy Volunteers
NCT07080710

State of the Art Immediate Implant Placement in the Premaxilla

Led by University Ghent · Updated on 2025-11-18

50

Participants Needed

2

Research Sites

343 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns. It will also learn about the safety and esthetic results of this treatment approach. The main questions it aims to answer are: Primary: How much buccal bone thickness remains one year after implant placement 1mm below the implant shoulder? Secondary: * How do patients rate pain, healing, and esthetics after treatment? * Are there any complications over the course of five years? * How much buccal bone thickness remains one year after implant placement 3mm and 5mm below the implant shoulder? * Marginal bone loss at one-year and five-year follow-up? * Peri-implant health at one-year and five-year follow-up? * Soft tissue changes at one-year and five-year follow-up? Researchers will compare treatment results in patients with intact bone sockets to those with damaged (non-intact) sockets. Participants will: * Receive a dental implant and temporary crown on the same day as the tooth extraction * Undergo guided, flapless surgery with bone and soft tissue grafting * Take antibiotics and anti-inflammatories for 4 days after surgery * Visit the clinic at 1 week, 3 months, 1 year, and 5 years for follow-up exams * Have X-rays, digital scans, and photos taken to measure bone and soft tissue changes * Answer questions about pain and esthetic satisfaction

CONDITIONS

Official Title

State of the Art Immediate Implant Placement in the Premaxilla

Who Can Participate

Age: 20Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 20 years old
  • Good oral hygiene defined as full-mouth plaque score 64 25%
  • Presence of one or more incisors, cuspids or premolars in the maxilla that need to be extracted for any reason with at least one neighboring tooth present
  • At least 3 mm bone available at the apical or palatal aspect of the alveoli as assessed on a three-dimensional radiograph to ensure primary implant stability
  • Written informed consent.
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Systemic diseases
  • Smoking
  • Suppuration
  • More than 1 mm gingival asymmetry between the failing teeth and contralateral teeth
  • Failing teeth outside the bone envelope as assessed on a three-dimensional radiograph
  • Untreated periodontal disease
  • Untreated caries lesions

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Ghent University

Ghent, East Flanders, Belgium, 9000

Actively Recruiting

2

Bv Dr. Cosyn

Zottegem, East Flanders, Belgium, 9620

Actively Recruiting

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Research Team

V

Véronique Christiaens, Phd

CONTACT

J

Jan Cosyn, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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