Actively Recruiting
State of the Art Immediate Implant Placement in the Premaxilla
Led by University Ghent · Updated on 2025-11-18
50
Participants Needed
2
Research Sites
343 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns. It will also learn about the safety and esthetic results of this treatment approach. The main questions it aims to answer are: Primary: How much buccal bone thickness remains one year after implant placement 1mm below the implant shoulder? Secondary: * How do patients rate pain, healing, and esthetics after treatment? * Are there any complications over the course of five years? * How much buccal bone thickness remains one year after implant placement 3mm and 5mm below the implant shoulder? * Marginal bone loss at one-year and five-year follow-up? * Peri-implant health at one-year and five-year follow-up? * Soft tissue changes at one-year and five-year follow-up? Researchers will compare treatment results in patients with intact bone sockets to those with damaged (non-intact) sockets. Participants will: * Receive a dental implant and temporary crown on the same day as the tooth extraction * Undergo guided, flapless surgery with bone and soft tissue grafting * Take antibiotics and anti-inflammatories for 4 days after surgery * Visit the clinic at 1 week, 3 months, 1 year, and 5 years for follow-up exams * Have X-rays, digital scans, and photos taken to measure bone and soft tissue changes * Answer questions about pain and esthetic satisfaction
CONDITIONS
Official Title
State of the Art Immediate Implant Placement in the Premaxilla
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 20 years old
- Good oral hygiene defined as full-mouth plaque score 64 25%
- Presence of one or more incisors, cuspids or premolars in the maxilla that need to be extracted for any reason with at least one neighboring tooth present
- At least 3 mm bone available at the apical or palatal aspect of the alveoli as assessed on a three-dimensional radiograph to ensure primary implant stability
- Written informed consent.
You will not qualify if you...
- Pregnancy
- Systemic diseases
- Smoking
- Suppuration
- More than 1 mm gingival asymmetry between the failing teeth and contralateral teeth
- Failing teeth outside the bone envelope as assessed on a three-dimensional radiograph
- Untreated periodontal disease
- Untreated caries lesions
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Ghent University
Ghent, East Flanders, Belgium, 9000
Actively Recruiting
2
Bv Dr. Cosyn
Zottegem, East Flanders, Belgium, 9620
Actively Recruiting
Research Team
V
Véronique Christiaens, Phd
CONTACT
J
Jan Cosyn, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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