Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07088250

Statins for Treatment of Primary Intracerebral Hemorrhage

Led by The Second Hospital of Anhui Medical University · Updated on 2025-07-28

264

Participants Needed

22

Research Sites

190 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The STOP ICH trial is a multicenter, prospective, randomized, open-label, blinded end-point (PROBE) study designed to assess the efficacy and safety of atorvastatin in patients with intracerebral hemorrhage (ICH) presenting within 3 to 24 hours of symptom onset.

CONDITIONS

Official Title

Statins for Treatment of Primary Intracerebral Hemorrhage

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of spontaneous intracerebral hemorrhage confirmed by CT scan
  • Age between 18 and 80 years
  • Hematoma located in the supratentorial region
  • Time from symptom onset or last known well to baseline CT between 3 and 24 hours
  • Atorvastatin treatment can start within 48 hours of symptom onset or last known well
  • Glasgow Coma Scale score of 9 or higher
  • Baseline hematoma volume between 5 and 35 mL
  • Signed informed consent obtained
Not Eligible

You will not qualify if you...

  • Intracerebral hemorrhage caused by trauma, tumor, aneurysm, arteriovenous malformation, vascular anomaly, hemorrhagic transformation of infarction, cerebral venous thrombosis, or related to anticoagulant use
  • Patients who have had or are planned for immediate surgical intervention
  • Pregnancy or breastfeeding
  • Use of oral anticoagulants within 1 month before symptom onset
  • Pre-stroke modified Rankin Scale score greater than 1
  • Known allergy to statins, active liver disease, liver dysfunction, or rhabdomyolysis
  • Terminal illness with life expectancy under three months or planned withdrawal of care

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 22 locations

1

Anqing First People's Hospital of Anhui Province

Anqing, Anhui, China

Actively Recruiting

2

Fuyang City Sixth People's Hospital

Fuyang, Anhui, China

Actively Recruiting

3

Fuyang Hospital of Anhui Medical University

Fuyang, Anhui, China

Actively Recruiting

4

Fuyang People's Hospital

Fuyang, Anhui, China

Actively Recruiting

5

Hefei Eighth People's Hospital

Hefei, Anhui, China

Actively Recruiting

6

Hefei First People's Hospital

Hefei, Anhui, China

Actively Recruiting

7

The Second Hospital of Anhui Medical University

Hefei, Anhui, China

Actively Recruiting

8

Huainan Xinhua Hospital

Huainan, Anhui, China

Actively Recruiting

9

The First Affiliated Hospital of Anhui University of Science and Technology (Huainan First People's Hospital)

Huainan, Anhui, China

Actively Recruiting

10

Huoqiu First People's Hospital

Lu'an, Anhui, China

Actively Recruiting

11

Shucheng People's Hospital

Lu'an, Anhui, China

Actively Recruiting

12

Si County People's Hospital

Suzhou, Anhui, China

Actively Recruiting

13

The First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

Actively Recruiting

14

Kaifeng Central Hospital

Kaifeng, Henan, China

Actively Recruiting

15

Xihua County People's Hospital

Zhoukou, Henan, China

Actively Recruiting

16

Xiangyang Hospital of Traditional Chinese Medicine

Xiangyang, Hubei, China

Actively Recruiting

17

The First People's Hospital of Chenzhou

Chenzhou, Hunan, China

Actively Recruiting

18

Yancheng First People's Hospital

Yancheng, Jiangsu, China

Actively Recruiting

19

Chengdu Western Hospital

Chengdu, Sichuan, China

Actively Recruiting

20

Panzhihua Central Hospital

Panzhihua, Sichuan, China

Actively Recruiting

21

Dazhu County People's Hospital

Dazhou, Sizhuan, China

Actively Recruiting

22

The Third Affiliated Hospital of Chong Qing Medical University

Chongqing, China

Actively Recruiting

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Research Team

Q

Qi Li

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Statins for Treatment of Primary Intracerebral Hemorrhage | DecenTrialz