Randomized Controlled Trial Comparing Venous Sinus Stenting and Neurosurgical Internal Ventricular Shunt for Papillary Edema in Idiopathic Intracranial Hypertension

What this Trial Is About

Researchers are studying idiopathic intracranial hypertension (HTICi), a condition mostly affecting young adults, especially women, caused by increased pressure inside the skull. This pressure can lead to swelling of the optic nerve (papillary edema), which may narrow the visual field and risk blindness. The study aims to compare two treatments to see which is more effective and safe for patients with moderate to severe vision problems after standard medical treatment has failed. The trial compares two procedures: neurosurgical internal ventricular shunting and endovascular venous sinus stenting. The shunt involves placing a catheter with an adjustable valve to help drain cerebrospinal fluid outside the skull. The stenting procedure uses a vascular device to open narrowed brain veins and requires six months of antiplatelet medication to improve fluid drainage. Both methods aim to reduce papillary edema and protect vision. Participants will be monitored for the resolution of papillary edema three months after treatment. The study involves assessments including imaging and clinical evaluations to measure treatment effects on eye swelling and vision. Researchers will track safety and effectiveness throughout the study, which began in 2022 and will continue until late 2026. Participants must provide consent and meet specific health criteria to join.

Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.