Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07458100

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Led by Peking University · Updated on 2026-04-21

464

Participants Needed

1

Research Sites

110 weeks

Total Duration

On this page

Sponsors

P

Peking University

Lead Sponsor

W

WU'AN FIRST PEOPLE'S HOSPITAL

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the effectiveness and cost-effectiveness of a digital mindfulness-based intervention in adults (aged 18-65) diagnosed with emotional disorders like depression or anxiety. The main questions it aims to answer are: * Does adding a digital mindfulness intervention to usual care help people recover from emotional disorders faster and more sustainably over two years? * Is this combined approach more cost-effective than usual care alone? Researchers will compare the group receiving the digital mindfulness intervention plus their usual treatment to the group receiving only their usual treatment to see if the intervention leads to better long-term recovery and represents good value for money. Participants in the intervention group will: * Attend eight weekly 2-hour online group mindfulness sessions. * Use a WeChat mini-program for 49 days of guided mindfulness exercises and daily tasks. * Patients who have not achieved reliable recovery after group retraining voluntarily participate in individual UP\&MIED counseling. * Complete regular questionnaires and interviews over two years to track their progress. All participants will continue to receive their usual medical care from their doctors throughout the study.

CONDITIONS

Official Title

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Diagnosed by an outpatient psychiatrist with an emotional disorder including depressive disorder, anxiety disorders (e.g., generalized anxiety disorder, panic disorder, agoraphobia, social anxiety disorder), obsessive-compulsive disorder, post-traumatic stress disorder, or eating disorders (e.g., anorexia nervosa, bulimia nervosa)
  • Symptom severity meeting thresholds: PHQ-9 score of 10 or higher or GAD-7 score of 8 or higher
Not Eligible

You will not qualify if you...

  • Current diagnosis of psychotic disorders or bipolar disorder
  • Current organic mental disorders, pervasive developmental disorders, severe cognitive impairment, or substance use disorders
  • Current suicide risk with PHQ-9 item 9 score greater than 2
  • Diagnosis of antisocial personality disorder
  • Severe medical illnesses affecting participation or requiring recent hospitalization
  • Previous participation in a systematic 8-week mindfulness course
  • Inability to access the internet

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University

Beijing, China

Actively Recruiting

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Research Team

D

Dongyang Chen

CONTACT

E

Elena Gomzyakova

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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