Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06432907

StereoEEG Motor Neuronal Potentials Decoding

Led by Research Center of Neurology, Russia · Updated on 2025-07-24

30

Participants Needed

1

Research Sites

133 weeks

Total Duration

On this page

Sponsors

R

Research Center of Neurology, Russia

Lead Sponsor

I

Institute of Higher Nervous Activity and Neurophysiology of RAS

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goals of this study are (1) to evaluate the rate of stereoEEG brain-computer interface (BCI) classification accuracy and (2) to collect the dataset of neuronal signals recorded from stereoEEG electrodes during motor performance, motor imagery or brain-computer interface control. The study enrolls hospitalised patients suffering from resistant epilepsy with already implanted intracranial stereoEEG electrodes for medical reasons (i.e. for preoperative localization of the epileptogenic foci). The number and location of electrodes are determined solely for the clinical purposes of stereoEEG monitoring and are not related to the protocol of the current study. After obtaining informed consent to participate in the study, each patient will participate in one experimental session lasting no more than 60 minutes, recording brain signals associated with hand movement, motor imagery, and BCI control. All tasks and instructions presented during the study session are not pro-epileptogenic and cannot provoke an epileptic attack. The experiments will take place in the patient's room, without interruption of observation by the department's medical staff. The data recorded in this study will be used to improve or develop new algorithms for decoding motor signals from deep brain structures for their potential use in invasive BCIs.

CONDITIONS

Official Title

StereoEEG Motor Neuronal Potentials Decoding

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients who have had stereoEEG electrodes implanted for medical reasons
  • Voluntary informed consent to participate in the study
  • Age from 18 to 70 years
Not Eligible

You will not qualify if you...

  • Patient refusal to participate in the study
  • Cognitive impairment that prevents following the study instructions
  • Severe visual impairment that does not allow viewing visual instructions on a computer screen
  • Upper limb paresis or other motor disorders
  • Pain in the hand of any etiology
  • Any acute diseases, exacerbation of chronic diseases, acute life-threatening conditions
  • Occurrence of an epileptic attack during the experiment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Research center of neurology, Department of neurorehabilitation and physiotherapy

Moscow, Russia, 125367

Actively Recruiting

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Research Team

O

Olesya A Mokienko, MD PhD

CONTACT

R

Roman Kh Lyukmanov, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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