Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT06665932

Stereotactic Radiotherapy of Prostate Cancer With Reduction of Safety Margins

Led by University Hospital Ostrava · Updated on 2024-11-12

100

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to reduce the PTV (Planning Target Volume) safety margins to 1-2 mm in stereotactic prostate radiotherapy for low- and medium-risk prostate cancers while maintaining a dose of 36.25 Gy in 5 fractions per day. By reducing the hems, the investigators expect a reduction of acute and late toxicity on the organs at risk, dominantly the urethra, bladder, penile bulb, and rectum, and an improvement in the quality of life.

CONDITIONS

Official Title

Stereotactic Radiotherapy of Prostate Cancer With Reduction of Safety Margins

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed localized prostate cancer without regional lymphadenopathy or distant metastases
  • Low or intermediate favorable risk prostate cancer
  • Staging according to NCCN recommendations: low risk requires no staging; intermediate risk requires CT of abdomen and pelvis
  • PSA level up to 15
  • Age over 18 years
  • Signed informed consent form
  • Suitable position of fiducials as determined by a physicist
Not Eligible

You will not qualify if you...

  • Histological type other than acinar adenocarcinoma
  • Presence of local lymphadenopathy or distant metastases
  • Dominant lesion in the periphery contacting or growing through the capsule
  • PSA level over 15
  • Unsatisfactory position of fiducials as determined by a physicist
  • Previous radiotherapy to the pelvic area

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia, 708 52

Actively Recruiting

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Research Team

J

Jiří Hynčica

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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