Actively Recruiting
Steroid Use in Treatment of Allergic Reactions to Food
Led by Johannes Trueck · Updated on 2026-01-27
160
Participants Needed
2
Research Sites
44 weeks
Total Duration
On this page
Sponsors
J
Johannes Trueck
Lead Sponsor
U
University Children's Hospital Basel
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary. When children have allergic reactions to foods, they are often given medications to relieve the symptoms. In addition to adrenaline and antihistamines, steroids are frequently administered in German-speaking Switzerland. However, it is unclear whether steroids are really helpful in this situation. To investigate this, the investigators are comparing two groups: one group receives additional steroids, and the other does not. Which treatment a participant receives is decided randomly, like flipping a coin. The study takes place during a pre-scheduled provocation test at the clinic. If an allergic reaction occurs, the usual emergency medications will be administered. Doctors will closely monitor how the reaction develops. No additional tests or visits are required. The results of this study could help improve allergy treatment in the future.
CONDITIONS
Official Title
Steroid Use in Treatment of Allergic Reactions to Food
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suspected or confirmed IgE-mediated food allergy
You will not qualify if you...
- Non-IgE mediated food allergies
- Non-food allergies
- Age outside the specified range (younger than 6 months or older than 18 years)
- Contraindications for an oral food challenge or oral steroid use within one week before the challenge
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
University Children's Hospital Basel
Basel, Basel, Switzerland, 4031
Actively Recruiting
2
University Children's Hospital, Zürich
Zurich, Canton of Zurich, Switzerland, 8008
Actively Recruiting
Research Team
J
Johannes Trück, PD Dr. med. DPhil
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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